Accrual monitoring in cardiovascular trials
نویسندگان
چکیده
منابع مشابه
Accrual monitoring in cardiovascular trials
Objective To provide brief guidance on how to design accrual monitoring activities in a clinical trial protocol. Setting Two completed clinical trials that did not achieve the planned sample size, the Cost of Strategies After Myocardial Infarction (COSTAMI) trial and the Biventricular Pacing After Cardiac Surgery (BiPACS) trial. Design A Bayesian monitoring tool, the constant accrual model,...
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PURPOSE The need to increase the number oncology clinical trials with sufficient enrollments is a well-known issue, particularly for trials targeting therapeutic applications. It is critical to identify early predictors of eventual study accrual achievement. EXPERIMENTAL DESIGN All nonpediatric phase I, I/II, II, and III therapeutic studies supported by the National Cancer Institute Cancer Th...
متن کاملEarly termination of cardiovascular trials as a consequence of poor accrual: analysis of ClinicalTrials.gov 2006–2015
OBJECTIVES To present a snapshot of experimental cardiovascular research with a focus on geographical and temporal patterns of early termination due to poor accrual. SETTING The Aggregate Analysis of ClinicalTrials.gov (AACT) database, reflecting ClinicalTrials.gov as of 27 March 2016. DESIGN The AACT database was searched for all cardiovascular clinical trials that started from January 200...
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هدف اصلی این تحقیق مقایسه و تمایز بین روشها و استراتژیهای خاص برای درک مطلب بهتر در زبان مادری و زبان دوم بوده است. در قدم اول میزان توانایی افراد در درک مطلب فارسی و انگلیسی اندازه گیری و سپس رده بندی شد. همچنین از دانش آموزان خواسته شد که در مورد روشها و استراتژیهایی که برای درک مطلب بهتر به کار برده بودند توضیح دهند. نتیجه این مرحله از تحقیق نشان داد که دانشجویان برای درک مطلب مطلوب در زبان ...
15 صفحه اولAcute stroke therapy trials: problems in patient accrual.
Temple University Hospital participated in a multicenter acute stroke trial but enrolled only one patient out of 192 screened over 2 years; other centers had similar difficulty in patient recruitment. We analyzed our screening data to determine which enrollment criteria created difficulties in recruitment and whether the problem was attributable to any single criterion or to combinations of cri...
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ژورنال
عنوان ژورنال: Open Heart
سال: 2017
ISSN: 2053-3624
DOI: 10.1136/openhrt-2017-000720